What Is Avandia?
The drug rosiglitazone, marketed by GlaxoSmithKline under the trade name Avandia, is an antidiabetic drug used to increase glycemic control. Rosiglitazone is used in conjunction with a diet and exercise program and sometimes one or more additional medications to treat type 2 diabetes. FDA reviewers are split between removing the drug from use and allowing continued distribution. Accordingly, the FDA has published a safety warning.
Side Effects Of Avandia
This medication may sometimes cause or worsen certain heart problems, such as congestive heart failure and heart attack. According to directions, the drug should not be prescribed or should be discontinued immediately if a patient has any of these symptoms: heart attack, increased cardiovascular event risk, macular edema, angina, disease of the arteries of the heart, disease of inadequate blood flow to the heart muscle, chronic heart failure, severe heart failure, chronic heart failure not suddenly currently controlled by medication, fluid in the lungs, drug-caused hepatitis, liver problems, osteoporosis, decreased calcification or density of bone, visible water retention, weight gain, abnormal liver function tests, broken bones, type 1 diabetes, retinal changes accompanying diabetes, low blood sugar and water retention.
Patients with congestive heart failure who have been treated with Avandia have an increased risk of cardiovascular events, and a greater increased risk of myocardial ischemia. Avandia can cause retention of fluid and it increases blood volume. Negative hepatic effects (hepatic dysfunction, unexplained nausea, vomiting, abdominal pain, fatigue, anorexia and/or dark urine, distressed liver enzyme levels) have also been documented.
Symptoms to look for:
- Heart failure
- Nausea, stomach pain, fever
- Allergic reaction: rash; hives; itching
- Tightness in the chest
- Shortness of breath
- Acute infection of the nose, throat or sinus
- Swelling or rapid weight gain
- Blurred vision or macular edema
- Liver problems (yellowing of the skin or eyes, vomiting)
- Swelling of mouth, face, throat, tongue
- Bone pain
- Increased blood flow leading to congestive heart failure
- Pulmonary edema
- Pleural effusion
FDA's Role In Avandia
[2-03-2011] The FDA is notifying the public that information on the cardiovascular risks (including heart attack) of the diabetes drug rosiglitazone has been added to the physician labeling and patient medication guide.
In addition to describing the cardiovascular risks, drug labels now state that rosiglitazone and rosiglitazone-containing medicines should only be used in these circumstances:
- In patients already being treated with these medicines
- In patients whose blood sugar cannot be controlled with other antidiabetic medicines and who, after consulting with their health care professional, do not wish to use pioglitazone-containing medicines, including Actos, Actoplus Met, Actoplus Met XR or Duetact (See Data Summary)
Call Our Office
Legal representation may be the only way for people harmed by Avandia to be compensated. The attorneys at Vititoe Law Group, in Southern California, have years of experience of dealing with the largest pharmaceutical companies.
If your loved one has suffered death, or if you have suffered a heart attack, cardiovascular disease, and you have been using Avandia, you should get a free case evaluation from Vititoe Law Group. You may be entitled to damages through a lawsuit. In any event, it is your duty as a user of this medicine to hold negligent companies responsible for the harm they cause.
For more information, call Vititoe Law Group at 818-851-1886.
Attorney Referrals: If you have a client injured by Avandia, we invite you to contact us.